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61.10,000 Hours with Claude Shannon (2017) (medium.com/the-mission)
157 points by bmcn2020 on Jan 20, 2021 | 82 comments
62.How to Start a Biotech Company on a Budget (blog.ycombinator.com)
145 points by flipchart on Jan 21, 2021 | 45 comments
63.SaaS We Happily Pay For (francescodilorenzo.com)
451 points by frankdilo on Dec 27, 2020 | 222 comments
64.What If You Could Do It All Over? (newyorker.com)
447 points by jonas21 on Dec 26, 2020 | 442 comments
65.Artificial Intelligence – The Revolution Hasn’t Happened Yet (2018) (medium.com/mijordan3)
278 points by seagullz on Dec 24, 2020 | 120 comments
66.An Overview of End-to-End Entity Resolution for Big Data (acolyer.org)
58 points by oedmarap on Dec 17, 2020 | 2 comments
67.How Payment Transaction Processing Works (privacy.com)
201 points by mooreds on Dec 7, 2020 | 79 comments
68.Data denormalization is broken (hackernoon.com)
171 points by endswapper on Sept 30, 2016 | 83 comments
69.I should have loved biology (jsomers.net)
800 points by jsomers on Nov 18, 2020 | 298 comments
70.Writing a book: is it worth it? (kleppmann.com)
642 points by vivekseth on Sept 29, 2020 | 287 comments
71.AI Expert Roadmap (am.ai)
195 points by simonpure on Nov 6, 2020 | 92 comments
72.How you could have come up with Paxos yourself (yshui.dev)
227 points by todsacerdoti on Oct 27, 2020 | 53 comments
73.Startup Financial Modeling: What is a Financial Model? (2016) (mathventurepartners.com)
229 points by aaronbski on Oct 22, 2020 | 49 comments
74.A Few Rules (collaborativefund.com)
233 points by merrier on Sept 24, 2020 | 81 comments
75.Ask HN: Suggestions for books about API design?
298 points by mcrittenden on Sept 5, 2020 | 90 comments
76.An F-22 test pilot on the Raptor's flight control system (thedrive.com)
240 points by clouddrover on July 12, 2020 | 131 comments
77.Explaining RNNs without neural networks (explained.ai)
126 points by parrt on July 10, 2020 | 7 comments
78.Show HN: Runnaroo – A new search engine (runnaroo.com)
380 points by chris_f on July 8, 2020 | 196 comments
79.TaBERT: A new model for understanding queries over tabular data (facebook.com)
153 points by speculator on July 3, 2020 | 25 comments
80.Crispr gene editing in human embryos wreaks chromosomal mayhem (nature.com)
72 points by YeGoblynQueenne on June 28, 2020 | 38 comments
81.Laura Deming, founder of the Longevity Fund, on being homeschooled (withprimer.com)
113 points by mksm on June 25, 2020 | 206 comments
82.Ask HN: Pitch your personal newsletter/blog with a one-liner
44 points by artembugara on June 21, 2020 | 58 comments
83.NoDesign.dev – Tools and resources for non-artistic developers (nodesign.dev)
762 points by uvic on June 8, 2020 | 160 comments
84.The death of corporate research labs (dshr.org)
445 points by fanf2 on May 20, 2020 | 248 comments
85.How I recorded an album on my own, in my room (medium.com/rodrigo.m.mesquita)
283 points by romes on March 16, 2020 | 110 comments
86.Who Can Name the Bigger Number? (1999) (scottaaronson.com)
100 points by lelf on Jan 21, 2020 | 43 comments
87.PySnooper: Never use print for debugging again (github.com/cool-rr)
675 points by cool-RR on April 22, 2019 | 168 comments

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