I broadly prefer JavaScript to TypeScript. TypeScript has it's place and is certainly useful in some scenarios (it's union type is so powerful) but I don't think I'd ever plan on coding exclusively in it. I've written code in OCaml and Rust too so I know what a good type system can do.

I think at least for UI work there is a lot of space for dynamic plumbing together of well typed components. Components in this case meaning actual UI components as well as modules of business logic or state management.