There isn't a yes/no answer for this. The disease has no cure and it is progressive, so saying that it worked for me means that it helps me in my day-to-day (fatigue level, vitality, post-exercise recovery, etc), but that's it. I understand that this is highly subjective from the outside, but after trying hundreds of different things I have developed a sixth sense to know what works for me.
The most important thing is food. In my case, a lowish-carb diet (around 100 grams/day). Only tubers and rice. I also do 2 keto cycles of 4-6 weeks every year based on this study [1]. It is a pain to go through this, but it seems to do some good in the long run.
The second thing is exercise. A combination of weight training and HIIT works great. There is some science behind this. In short: satellite cells are mutation free. Weight training activates them and aerobics makes them "reproduce". This way, I can offset the replication advantage that mutant cells have ("clonal expansion", the force that makes the disease progressive).
Third, supplements.
Plain CoQ10 in some formulation that improve bio-availability (p.e. Jarrow's Q-absorb). 100-200 mg/day. I can't see additional benefits in larger doses.
Plain non-flush niacin (500 mg/day). There is a recent study for this [1] with actual human beings with the very same disease that I have.
I also take curcumin and several forms of magnesium daily. They both seem to work.
