A relative of mine lost some degree of eyesight (ischemic optic neuropathy) a bit after going on antidepressants and I always wondered if it was a side effect of lowered blood flow/pressure to the eye. Interesting to see it investigated for other drugs.

If those nerves lose oxygen for even a little while overnight, you lose (some) sight and never get it back.

Ozempic flew off the shelves in my region 2 years ago when people thought it was a risk-free way to lose weight. More than half had side effects but still insisted it was working.

You can't trick nature.

You can "trick" chemistry we just don't know yet the rest of interactions it will have on such a complex system

“Importantly, the study does not prove causality, and the researchers don't know why or how this association exists, and why there was a difference reported in diabetic and overweight groups.”