Perhaps, but I wonder how much having so many different languages contributes to that. In the US, most people all speak English (though there's a growing Spanish-speaking population, but even here most younger ones probably end up being bilingual), so there's not that much to do for your company to do business in all 50 states, depending on just how much interaction with state governments you require. And state laws are all pretty similar usually. Not so in the EU.
Lack of a common language must be a factor in scaling - the amount of effort printing required information in different languages is already an overhead (e..g instructions on medications).
Also in the US, somebody in California can give telephone support to somebody in Rhode Island; not so easy to get somebody in Sweden to give telephone support to somebody in Italy though.
