Definitely. I'd just be happy if you could get a mechanical keyboard that uses the layout that MS uses for its ergonomic keyboards, with the split keys and the height gently swelling in the center where the split is. (Look at the Natural Keyboard 4000 to see what I'm talking about: http://www.microsoft.com/hardware/en-us/p/natural-ergonomic-...)
Once you get used to typing on a keyboard that uses this layout, going back to a standard flat and un-split layout feels slow and painful. I love mechanical switches, but not enough to give up the much better layout of the Natural keyboards to get them.
The Natural 4000 is a bit hit or miss. I've had 3; two were excellent, but one is merely acceptable. The action of the keys isn't as smooth, and the space bar initially required a slightly firmer press. The space bar seems to have loosened up over time, though, and I got used to the key feel quicker than I was expecting - but typos ARE much more frequent on that keyboard.
The inconsistency is a shame, because as a keyboard I really rate it. Good shape, comfy palm rests, standard layout, unintrusive media keys, and the stupid (but seemingly inevitable) F-Lock feature starts out disabled.
The action is not quite as nice as the previous Natural Pro model, but it's a lot quieter...
Once you get used to typing on a keyboard that uses this layout, going back to a standard flat and un-split layout feels slow and painful. I love mechanical switches, but not enough to give up the much better layout of the Natural keyboards to get them.