We use computers all the time. For the average consumer, that mouse is pretty nice. I don't mind using mine when I'm surfing or just doing email. Editing text and doing Photoshop with the Mighty Mouse is hideous. I use a Logitech Anywhere MX - the thing will track on glass.
From my limited use of it: clicking with it--since the whole body clicks--moves the cursor out of place, such that I lose precision clicking. The scroll ball is atrocious. It gets dirty and loses function, and it's not easy to clean.
I work at a place with about 10-20 Macs. The batteries die faster than I can replace them. I get about 20 batteries per month and we churn through them. I gave up trying to get people to turn them off, put them all in a draw and a helpful colleague replaced all with el cheapo MS corded mice. Much better.